Mal - Bugs Bunny
Zoe - Marvin the Martian **See footnote**
Jayne - Yosemite Sam
Wash - Daffy Duck
Book - Sylvester
Inara - Pepé Le Pew
Kaylee - Tweety Bird
Simon - Porky Pig
River - Wile E. Coyote
Serenity - Road Runner
Reavers - Taz, the Tasmanian Devil
Lenore, Mr Universe's Love-bot - Miss Prissy
Mr Universe - Foghorn Leghorn
The Operative - Elmer Fudd

**footnote - I apologize for criticizing this parody, but... Gina Torres would be better served if Zoe was Lola Bunny, a female, rather than Marvin the Martian, a male. Lola Bunny, the only Looney Tunes character created after the Golden Age of American animation, first appeared in 1996 for "Space Jam." Furthermore, Zoe and Mal are both war heroes/survivors; they both should be of the same species: bunny rabbits. If you want to see Zoe as Lola Bunny, there is a drawing at http://thedaffynated1.deviantart.com/art/Zoe-Washbugs-58219610

Some of them are hilarious and some are fitting... Although I think that Wile E. Coyote would make a better Simon than Porky Pig. I'm not sure who would replace River, though, and who could be Porky Pig instead.

Sylvester Sam as Jayne and Pepe le Pew as Inara though... PRICELESS.

Oh my dear and fluffy Lord. This is just so so...wrong.

But funny. TweetyKaylee works. And the Tasmanian Reavers...

Very funny

I wonder if a "Family Guy/Firefly "metamorphasis would work...has THAT been done already???

HI-larious, Funny stuff. Yosemite Same as Jayne - freaking awesome! Daffy as Wash - Priceless! Tweety as Kaylee - LOL

....and the Tasmanian Reavers - perfect.

SGG

Gotta love Daffy Duck as Wash, Bugs as Mal, Taz as the Reavers, and Yosemite Sam as Jayne. They are god fits. As for the rest, not so good but still a great drawing.

Bytemite wrote, "...I think that Wile E. Coyote would make a better Simon than Porky Pig. I'm not sure who would replace River, though..."

Just visualize putting a green frog in River's green dress that she wears to fight Reavers. River could be Michigan J. Frog. Besides being a Looney Tune character that dances, Michigan was the official mascot of the WB Television Network, where both "Buffy" and "Angel" premiered. http://en.wikipedia.org/wiki/Michigan_J._Frog

Tweety-Kayle FTW!