REAL WORLD EVENT DISCUSSIONS

FOR SCIENCE!

POSTED BY: FREMDFIRMA
UPDATED: Sunday, April 15, 2012 19:46
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Friday, April 13, 2012 3:01 AM

FREMDFIRMA



Well, mostly for Byte and Siggy, but sharing some science stuff...
(This is actual scientific journal type stuff, mind - heavy reading)

Conservative thought linked to lazy thinking, sure to rile up the rightwingnuts, but proper metholodogy on this one.

Low-Effort Thought Promotes Political Conservatism
http://psp.sagepub.com/content/early/2012/03/16/0146167212439213.abstr
act


And this caught my eye, as it's also peer-reviewed and seems to establish a link between environmental toxins, diet and autism, and one of the big culprits that stands out is High Fructose Corn Syrup, the introduction and expansion of which does *seem* to correllate with the increase, once one takes better and more refined diagnosis over time into account.

A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States
http://www.clinicalepigeneticsjournal.com/content/4/1/6/abstract

Mind you, both of these are at the very barest edge of my competence, I get the gist, but this stuff is way the hell out of my field so the details aren't something I could discuss outside of a laymans viewpoint.

Also, U of M wants to do some more investigation of "Fisher King Effect" which'll be interesting - the notion that some people can influence other people or situations simply by being physically present, and the current experiments this weekend will involve distance, line of sight and potential range/radius of effect.

-Frem

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Friday, April 13, 2012 3:28 AM

GEEZER

Keep the Shiny side up


Quote:

In Study 1, alcohol intoxication was measured among bar patrons; as blood alcohol level increased, so did political conservatism (controlling for sex, education, and political identification).

In Study 2, participants under cognitive load reported more conservative attitudes than their no-load counterparts.

In Study 3, time pressure increased participants’ endorsement of conservative terms.

In Study 4, participants considering political terms in a cursory manner endorsed conservative terms more than those asked to cogitate; an indicator of effortful thought (recognition memory) partially mediated the relationship between processing effort and conservatism.



So people who don't drink, don't have anything else to think about, don't have anything to get done, and have a lot of spare time to deliberate tend to be more liberal?



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Friday, April 13, 2012 3:28 AM

M52NICKERSON

DALEK!


The second study is very interesting in finding that the increase of Autism in the US is not linked to Mercury exposure from most of the that have been discussed before, such as thimersol, but maybe indirectly from taking in High Fructose Corn Syrup (HFCS).

Basically it is stating that taking in HFCS can cause mineral imbalances which can make the body more susceptible to the effects of inorganic mercury and fructose. Those effects on genetic expression can be passed on to the next generation.


I do not fear God, I fear the ignorance of man.

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Friday, April 13, 2012 4:55 AM

BYTEMITE


Well. I think that there's a lot of potential environmental factors out there. HFCS is a big one, of course, and Mercury spread by industrial and smelting operations is ALWAYS a concern. I would say that mercury tends to be more associated with a lot of physical birth defects (which is why pregnant women are told not to eat fish, unsafe levels of bioaccumulation), but exposure does potentially damage nerve cells, and at risk children might have a specific susceptibility, possibly like an allergy, to the thimerosol when they're exposed to it. If so, we really ought find the specific point of vulnerability and screen for it before administering vaccines. Same thing for people with a susceptibility to Guillian Barre syndrome. Genetic sequencing, blood samples to check for elevated levels of anti-bodies and so on. We should also try to advance our medical technology instead of allowing it to stagnate - reliance on the human immune system and antibiotics for bacteria is haphazard at best.

Sig says that there's a developmental and gastro-intestinal protein associated with autism, I can believe that's involved in a number of cases. But I also think that there are forms of autism that aren't associated with anything gastrointestinal - problems perhaps caused by chemical exposure that mimic the more natural form of autism.

This mineral imbalance and transferable HFCS susceptibility aspect sounds to me like a good starting ground. I like this part in particular - proposing a method of action is I think essential to take a hypothesis from simple statistics and link it to concrete science and chemistry.

Quote:

Figure 1 shows the Mercury Toxicity model that provides a macroepigenetic explanation of
how human neurodevelopment can be adversely impacted when gene expression is altered by
dietary transcription factors such as zinc insufficiency or deficiency, or by exposure to toxic
substances found in our environment, such as the heavy metals mercury and copper [4].
Elimination of heavy metals requires the expression of the metallothionein (MT) gene, which
synthesizes the Zn-dependent metal binding protein metallothionein [15]. With dietary zinc
(Zn) loss and copper (Cu) gain from the consumption of high fructose corn syrup (HFCS)
[16], metabolic processes required to eliminate heavy metals are impaired in children with
autism [4]. Mercury has been found in samples of high fructose corn syrup and is allowable
in trace amounts in certain food colors so long as the concentration does not exceed one
part per million [17,18]. Mercury (Hg) and specific other heavy metals, including lead (Pb),
copper (Cu), cadmium (Cd), silver (Ag) and bismuth (Bi), are capable of displacing the Zn
atom in the MT protein molecule [15]. This ‘pathogenic’ displacement of Zn impairs the MT
molecule and its ability to pick up the heavy metal and carry it out of the body. If the diet is
deficient in Zn or the absorption of Zn is impaired, then the body may not produce enough
MT protein to carry and excrete the heavy metal load [19,20]. Children with autism may be
Zn deficient and often have MT dysfunction [21-23]. Because of their diminished capacity to
excrete toxic heavy metals, the severity of their condition is associated with their toxic metal
burden [24]. This macroepigenetic model proposes that autism prevalence is related to the
consumption of HFCS and the overall exposure to Hg in the U.S. [4]. However, other dietary
factors associated with the consumption of HFCS may further contribute to the development
of autism in the U.S.


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Friday, April 13, 2012 6:24 AM

FREMDFIRMA



Ain't just that HFCS can make em more susceptible, it's also that HFCS often contains substantial amounts of mercury due to cross-contamination via the process in which it is made - and even if any individual sample contains very little, given that it's in almost EVERY BLOODY THING ON THE SHELF....
That'll add up.

Reference links.
http://www.washingtonpost.com/wp-dyn/content/article/2009/01/26/AR2009
012601831.html

http://motherjones.com/environment/2009/07/corn-syrups-mercury-surpris
e

http://www.huffingtonpost.com/christopher-gavigan/parents-mercury-cont
amina_b_160984.html

http://blogs.ajc.com/better-health/2009/09/30/ask-dr-h-mercury-contami
nation-and-high-fructose-corn-syrup
/

-Frem

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Friday, April 13, 2012 8:24 AM

M52NICKERSON

DALEK!


That's true and it does not help, but without the action of the HFCS that exposure may not matter...in terms of autism.

I do not fear God, I fear the ignorance of man.

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Friday, April 13, 2012 11:22 AM

BYTEMITE


And exposure to HFCS during pregnancy doesn't make every child automatically susceptible to mineral imbalances and autism, so there's probably something happening on the individual level.

But, I agree, HFCS is bad, and this is also a good start to exploring this possibility.

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Friday, April 13, 2012 11:40 AM

KWICKO

"We'll know our disinformation program is complete when everything the American public believes is false." -- William Casey, Reagan's presidential campaign manager & CIA Director (from first staff meeting in 1981)


Quote:

Originally posted by Geezer:
Quote:

In Study 1, alcohol intoxication was measured among bar patrons; as blood alcohol level increased, so did political conservatism (controlling for sex, education, and political identification).

In Study 2, participants under cognitive load reported more conservative attitudes than their no-load counterparts.

In Study 3, time pressure increased participants’ endorsement of conservative terms.

In Study 4, participants considering political terms in a cursory manner endorsed conservative terms more than those asked to cogitate; an indicator of effortful thought (recognition memory) partially mediated the relationship between processing effort and conservatism.



So people who don't drink, don't have anything else to think about, don't have anything to get done, and have a lot of spare time to deliberate tend to be more liberal?






More like, people who aren't drunks and who actually take the time to think things through are more liberal.

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Friday, April 13, 2012 1:20 PM

BIGDAMNNOBODY


And we certainly know which side of the fence people without a sense of humor are on.

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Friday, April 13, 2012 2:32 PM

M52NICKERSON

DALEK!


Quote:

Originally posted by BYTEMITE:
And exposure to HFCS during pregnancy doesn't make every child automatically susceptible to mineral imbalances and autism, so there's probably something happening on the individual level.

But, I agree, HFCS is bad, and this is also a good start to exploring this possibility.



Absolutely!

I do not fear God, I fear the ignorance of man.

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Friday, April 13, 2012 2:33 PM

M52NICKERSON

DALEK!


Quote:

Originally posted by BigDamnNobody:
And we certainly know which side of the fence people without a sense of humor are on.



The left, we laugh at the right all the time!

I do not fear God, I fear the ignorance of man.

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Sunday, April 15, 2012 7:46 PM

RIONAEIRE

Beir bua agus beannacht


I think we can all agree on that HFCS is in wayyyyyyy too many things and since its fake its not really good for the body. I also think that what we currently call "autism" is sooooooooooo many different things that all seem to get stuck under one umbrella, I wish it wasn't so broad and things had more specific names. But I hope they study this angle more.

I assume you're my pal until you let me know otherwise.

"A completely coherant River means writers don't deliver" KatTaya.

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